Psilocybin Relieves Depression

Psilocybin showed significant effectiveness against major depression, much more powerful than psychotherapy or antidepressants.

Screened participants were given a moderately high dose of 20mg/70kg (perhaps 4.5 grams mushrooms for a 70kg person) and a week and a half later were given a high dose of 30mg/70kg (perhaps 6.7 grams / 70 kg).

"These data expand the findings of previous studies involving patients with cancer and depression as well as patients with treatment-resistant depression by suggesting that psilocybin may be effective in the much larger population of MDD. Further studies are needed with active treatment or placebo controls and in larger and more diverse populations."