Psilocybin and Depression

Increasing evidence from trials with psilocybin, LSD, and ayahuasca indicate psychedelics may be useful in treating depression.  A recent study showed "marked" results in patients with a background of moderate to severe depression that had not responded to traditional methods.

Also: an editorial on Psychedelics Can Treat Depression: Why Outlawing Psychedelics is the Worst Censorship of Medicine in Human History.